Planning councillors passed plans for a light industrial building to be built behind a home at 73 Peterborough Road, Crowland.
The proposed building is 17x10 metres and can only be used by the applicants, Mr and Mrs Nigel Powell.
It will be used for camper van hire together with an upholstery and trimming service.
Mr Powell told the planning committee the business was for vintage VW camper vans.
He said: “We feel much more secure if we are on site 24/7 as opposed to leaving them in an industrial unit somewhere.”
A condition agreed by South Holland’s planning committee also limits the number of camper vans on site at any one time to three.