Pupils at Crowland site of the University Academy Holbeach have raised nearly £580 for a cancer unit in memory of their headteacher, Jo Fletcher.
Mrs Fletcher lost her life to cancer in 2011.
The disease has touched the lives of many at the school, including staff member Ruth Ellis who bravely battled breast cancer in 2009 while in the care of the former Peterborough District Hospital.
Mrs Ellis said: “It was a difficult chapter in my life but was made easier by the support I received.
“It is important for pupils to understand that people can beat this illness and by holding these fundraising events it brings a cure ever closer.”
Her own treatment involved surgery, chemotherapy and radiotherapy.
Mrs Ellis has spearheaded fundraising at the school alongside science technician Tania Hambleton.
Recent fundraising events included a cake stall, quizzes and a huge Christmas raffle.
Prizes for the raffle were donated by staff, pupils and businesses – and were made up into themed hampers with titles such as In the Pink, Christmas Cheer and Yummy Tummy.
The school held a special assembly at which Mrs Ellis presented £578.04 to Claire Hall, a breast care nurse from Peterborough City Hospital oncology unit.
The assembly was attended by invited guests from the community as well as governors.
Mrs Hambleton paid tribute to the school’s “amazing amount raised” as only 77 pupils remain on roll.
This is the final year at the Crowland site before pupils switch to Holbeach in September 2013.
Mrs Ellis and Mrs Hambleton thanked local businesses and all who supported the fundraising events.
Among those donating to the raffle were Crowland Garden Centre, Lincolnshire Co-operative, Abbey Bakery, Crowland Show Committee and The Chocolate Pizza Company.